Drag-and-drop synthetic DNA self-assembly — zmescience.com

Source: http://www.zmescience.com/medicine/drag-and-drop-drug-design-dna-assembly-43243/

Researchers at Parabon NanoLabs have developed an unique tool that allows scientists to use an intuitive drag-and-drop computer interface, much like in any other 3-D CAD software like Catia or AutoCAD, together with DNA self-assembly techniques, to develop and test new drugs much faster.

Called the Parabon Essemblix Drug Development Platform, the tool can be used to design molecular pieces with specific, functional components.

Some molecules are currently used to identify cancer cells, others are capable of latching to cancer cells, while others kill them.

Combining them renders mixed effects.

After the design is saved, a cloud supercomputing platform that uses proprietary algorithms to search for specific sets of DNA sequences that can self-assemble those components.

With a proper sequence in place that works, scientists chemically synthesize trillions of identical copies of the designed molecules.

The development phase of the drug is now cut to weeks even days instead of months or even years compared to conventional trial and error.

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Published in: on 07/12/2012 at 20:55  Leave a Comment  

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